rsHRF: A toolbox for resting-state HRF estimation and deconvolution

rsHRF: A toolbox for resting-state HRF estimation and deconvolution

Blog Article

The hemodynamic response function (HRF) greatly influences the intra- and inter-subject variability of brain activation and connectivity, and might confound Nail Lacquer the estimation of temporal precedence in connectivity analyses, making its estimation necessary for a correct interpretation of neuroimaging studies.Additionally, the HRF shape itself is a useful local measure.However, most algorithms for HRF estimation are specific for task-related fMRI data, and only a few can be directly applied to resting-state protocols.Here we introduce rsHRF, a Matlab and Python toolbox that implements HRF estimation and deconvolution from the resting-state BOLD signal.We first provide an overview of the main algorithm, practical implementations, and then demonstrate the feasibility and usefulness of rsHRF by VITAMIN COOLER PEACH MANGO validation experiments with a publicly available resting-state fMRI dataset.

We also provide tools for statistical analyses and visualization.We believe that this toolbox may significantly contribute to a better analysis and understanding of the components and variability of BOLD signals.